NOT KNOWN FACTUAL STATEMENTS ABOUT NR1-SITE

Employing this strategy, Kalbaugh et al. assigned affinity and efficacy roles to positions in the LBDs of the NR1 and NR2A NMDAR subunits. In situ mutation of residues in direct contact with certain ligand afflicted both efficacy and affinity, although positions that stabilize the closed cleft conformation and not using a immediate ligand conversat